【少看电视多吃果蔬 可降低遗传性肥胖风险】

【少看电视多吃果蔬 可降低遗传性肥胖风险】伦敦大学一项关于环境与遗传性肥胖的研究发现,生活在习惯于多吃水果、蔬菜,较少看电视的家庭中的儿童,遗传学因素造成其肥胖的风险较低,反之,遗传学因素占肥胖风险比例较高。数据来自对925对同卵和异卵双胞胎的调查,研究中评估累遗传和环境对儿童早期体重轨迹的影响。研究结果表明基因对肥胖的影响可因环境的不同而不同,健康家庭环境对儿童体重指数BMI的影响可以超越遗传对其的影响。

A healthy home with more fruits and vegetables and less time watching TV can cut children's genetic obesity risks by HALF, study finds

  • Researchers studied 925 pairs of twins to determine if a child's obesity risk was influenced by genetics or the environment
  • Genetics accounted for 86 percent of obesity risk when a child lived in a home with less healthy food and more time spent watching TV
  • But in homes with fruits and vegetables and more time spent exercising, genetics only accounted for 39 percent of the risk 

A healthy home environment could cut a child's genetic risk for obesity by half, a new study has found.

Genetics put some people at greater risk of obesity than others, and, because fraternal twins share 50 percent of their genes and identical twins share 100 percent of their DNA, their inherited risks should be similar.

Scientists from University College London conducted the research on both types of twins, they found that the environment could actually alter how much influence those obesity genes exert on body mass index (BMI).

When children lived in a home with less access to fruits and vegetables and more time spent watching TV, genetics accounted for 86 percent of their obesity risk.

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But in homes with more healthy foods and time spent participating in physical activities, genetics only accounted for 39 percent of their obesity risk.

The team says its findings show that genes can actually be influenced and overridden by the home environment.

For the study, the team look at 925 pairs of twin from the British Gemini cohort between July and October 2013 and followed up June 2018.

Run by the University College London, the cohort evaluates both genetic and environmental influences on the trajectory of weight in early childhood.

Researchers then collected data on BMI and how 'obesogenic' their home environments were.

BMI is a measure of body fat based on height and weight and obesogenic' is the likelihood of causing obesity. This included if they keep fruits and vegetables in the home, time spent exercising, and time spent watching television.

Each home was then given a score indicating whether it was a 'high-risk' or 'low-risk' environment for obesity.

The findings showed that 508 pairs of twins were living in 'low-risk', healthier environments and 417 pairs were living in 'high-risk', less healthy environments.

What they found was a surprising relationship between genes and the environment.

'The finding supports a theory, developed by our group, that genetic susceptibility to obesity will be most highly expressed when individuals are living in a obesogenic environment that encourages excess consumption and low physical activity,' said first author Dr Stephanie Schrempft, a professor at University College London.

'In other words: "the genetic background loads the gun, but the environment pulls the trigger".'

In the high-risk home environments, identical twins were much more similar in BMI than fraternal twins, indicating more of a genetic influence.

However, in the low-risk home environments, both types of twins were similar in BMI, which, the authors say, shows a healthy home environment can override genetic influence.

Genetics accounted for 86 percent of a risk for obesity for children in the high-risk environments.

But in the low risk environment, genetic differences only accounted for 39 percent of a child's risk for obesity.

The rate of childhood obesity has tripled since the 1970s, affecting one in five children in the US and 14 percent of those between ages two and four years old, according to data from the Centers for Disease Control and Prevention.

Childhood obesity is now the number one health concern among parents in the US, topping drug abuse and smoking.

Obesity raises the risk of numerous diseases from type 2 diabetes to endometrial cancer, meaning more sick people and higher medical costs in the future, according to a 2012 report from the Trust for America's Health and the Robert Wood Johnson Foundation.

Currently, the estimated annual health care costs of obesity-related illness are an astonishing $190.2 billion or nearly 21 percent of annual medical spending in the US.

Childhood obesity alone is responsible for $14 billion in direct medical costs.

原文链接:https://www.dailymail.co.uk/health/article-6257787/A-healthy-home-cut-childrens-genetic-obesity-risks-HALF-study-finds.html


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