#科技头条#【逆天!有味觉有嗅觉的”生物芯片“】

#科技头条#【逆天!有味觉有嗅觉的”生物芯片“】 哥伦比亚大学电子工程教授Ken Shepar 研发出一种融合生命和非生命系统的生物芯片,该芯片以CMOS集成电路与ATP-harvesting 生物电池为原型,结合CMOS集成电路和一个由ATP离子泵制成的人工脂质双分子层膜来创建,带来生物和硅更有效融合的新时代。http://www.looooker.com/?p=20602

Researchers unveil first biologically powered 'cyborg' computer chip and say it could be able to taste and smell

  • Columbia University developed a biochip with living and nonliving systems
  • CMOS integrated circuit with an ATP-harvesting biocell for prototype
  • Performing on a molecular level, able to isolate the desired function 

For the first time, scientist have developed an electronic chip made of both biological and solid-state components.

It could lead to a new generation of 'cyborg' chips blending senses such as taste or smell with traditional electronic components.

They combined solid-state complementary metal-oxide-semiconductor (CMOS) integrated circuit with an artificial lipid bilayer membrane made of ATP-powered ion pumps to create a 'biochip'.

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(a) Illustration depicting biocell attached to CMOS integrated circuit. (b) Illustration of membrane in pore containing sodium–potassium pumps. For the first time, scientist have developed an electronic chip that is both biological and solid-state components.

(a) Illustration depicting biocell attached to CMOS integrated circuit. (b) Illustration of membrane in pore containing sodium–potassium pumps. For the first time, scientist have developed an electronic chip that is both biological and solid-state components.

WHAT COULD IT BE USED FOR?

The ability to build a system that combines the power of solid-state electronics with the capabilities of biological components has great promise, the researchers say.

'You need a bomb-sniffing dog now, but if you can take just the part of the dog that is useful -- the molecules that are doing the sensing -- we wouldn't need the whole animal.'

This breakthrough study was led by Ken Shepard, Lau Family Professor of Electrical Engineering and professor of biomedical engineering at Columbia University.

'In combining a biological electronic device with CMOS, we will be able to create new systems not possible with either technology alone,' said Shepard.

'We are excited at the prospect of expanding the palette of active devices that will have new functions, such as harvesting energy from ATP, as was done here, or recognizing specific molecules, giving chips the potential to taste and smell.'

'This was quite a unique new direction for us and it has great potential to give solid-state systems new capabilities with biological components.'

Although there has been a breakthrough with these new findings, Shepard said that CMOS solid-state electronics do not have the ability to perform or replicate certain functions of living systems, such as tasting, smelling and the use of biochemical energy sources.

Living systems perform these functions with their own versions of electronics based on lipid membranes and ion channels and pumps, which act as a kind of biological transistor.

Charge is produced in ion form, which carries energy and information, and the ion channels control the flow of ions across cell membranes.

The breakthrough could see systems that blend silicon and biology far more effectively

The breakthrough could see systems that blend silicon and biology far more effectively

Solid-state systems, such as those in computers and communication devices, use electrons; their electronic signaling and power are controlled by field-effect transistors.

Living systems store energy in potentials across lipid membranes, but in this case they were create through the action of ion pumps.

ATP is used to transport energy from where it is generated to where it is consumed in the cell.

The team packaged a CMOS integrated circuit with an ATP-harvesting 'biocell' to begin building the prototype.


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